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Article

Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons.

Stem cell reports - 12 Sept 2017

Pereira Maria, Birtele Marcella, Shrigley Shelby, Benitez Julio Aguila, Hedlund Eva, Parmar Malin, Ottosson Daniella Rylander

Abstract excerpt

Converting resident glia into functional and subtype-specific neurons in vivo by delivering reprogramming genes directly to the brain provides a step forward toward the possibility of treating brain injuries or diseases. To date, it has been possible to obtain GABAergic and glutamatergic neurons via in vivo conversion, but the precise phenotype of these cells has not yet been analyzed in detail. Here, we show...

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Identifiers

PMID: 28844658
DOI: 10.1016/j.stemcr.2017.07.023
PMCID: PMC5599255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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