Article
The mutational oncoprint of recurrent cytogenetic abnormalities in adult patients with de novo acute myeloid leukemia.
Leukemia - 1 Oct 2017
Eisfeld A-K, Mrózek K, Kohlschmidt J, Nicolet D, Orwick S, Walker C J, Kroll K W, Blachly J S, Carroll A J, Kolitz J E, Powell B L, Wang E S, Stone R M, de la Chapelle A, Byrd J C, Bloomfield C D
Abstract excerpt
Recurrent chromosomal abnormalities and gene mutations detected at the time of diagnosis of acute myeloid leukemia (AML) are associated with particular disease features, treatment response and survival of AML patients, and are used to denote specific disease entities in the World Health Organization classification of myeloid neoplasms and acute leukemia. However, large studies that integrate cytogenetic and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.