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Cytogenetics and genomics of acute myeloid leukemia.

Best practice & research. Clinical haematology - 1 Mar 2024

Snaith Oraine, Poveda-Rogers Corey, Laczko Dorottya, Yang Guang, Morrissette Jennifer J D

Abstract excerpt

The diversity of genetic and genomic abnormalities observed in acute myeloid leukemia (AML) reflects the complexity of these hematologic neoplasms. The detection of cytogenetic and molecular alterations is fundamental to diagnosis, risk stratification and treatment of AML. Chromosome rearrangements are well established in the diagnostic classification of AML, as are some gene mutations, in several international...

Topics

Humans
Leukemia, Myeloid, Acute
Chromosome Aberrations
Mutation
Genomics
Cytogenetic Analysis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38490763
DOI: 10.1016/j.beha.2023.101533

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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