Emerging molecular predictive and prognostic factors in acute myeloid leukemia.

Abstract excerpt

Recurrent cytogenetic abnormalities have provided the backbone for prognosticating acute myeloid leukemia and predicting response to consolidative therapies for decades. However, more than 45% of acute myeloid leukemia patients have normal cytogenetics on both karyotype and fluorescence in situ hybridization at diagnosis. Increasingly utilized next-generation sequencing has led to the discovery of numerous...

Topics

• Acute Disease
• Genetic Predisposition to Disease
• Humans
• Leukemia, Myeloid
• Mutation
• Neoplasm Recurrence, Local
• Outcome Assessment, Health Care
• Prognosis
• Risk Factors
• Survival Analysis