Article
Driver mutations in acute myeloid leukemia.
Current opinion in hematology - 1 Mar 2020
Kishtagari Ashwin, Levine Ross L, Viny Aaron D
Abstract excerpt
PURPOSE OF REVIEW: The mutational landscape of acute myeloid leukemia (AML) has revised diagnostic, prognostic, and therapeutic schemata over the past decade. Recurrently mutated AML genes have functional consequences beyond typical oncogene-driven growth and loss of tumor suppresser function. RECENT FINDINGS: Large-scale genomic sequencing efforts have mapped the complexity of AML and trials of mutation-based...
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