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Article

Systematic identification of an integrative network module during senescence from time-series gene expression.

BMC systems biology - 15 Mar 2017

Park Chihyun, Yun So Jeong, Ryu Sung Jin, Lee Soyoung, Lee Young-Sam, Yoon Youngmi, Park Sang Chul

Abstract excerpt

BACKGROUND: Cellular senescence irreversibly arrests growth of human diploid cells. In addition, recent studies have indicated that senescence is a multi-step evolving process related to important complex biological processes. Most studies analyzed only the genes and their functions representing each senescence phase without considering gene-level interactions and continuously perturbed genes. It is necessary to...

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Identifiers

PMID: 28298218
DOI: 10.1186/s12918-017-0417-1
PMCID: PMC5353876

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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