Article

Network topology and evolution of the gene co-expression of T-cells during immuno-senescence

2021-09-02

Abstract excerpt

To better understand the potential impact of the gene expression network structure on the dynamics of immune-senescence and defects of cell functions during aging, we investigated network structures in both young and old individuals. We analyzed the gene co-expression networks (GCNs) derived from an aging signature of 130 immune-related genes obtained from CD3+ T-cell splenocytes extracted from FVB/N, C57BL/6N, an...

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Literature Corpus work: 9d8a0b78-4296-5e96-a5d4-dd5d1fa87361
DOI: 10.1101/2021.09.01.458500

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