Article

Robust senescence evaluation by transcriptome-based hUSI to facilitate characterizing cellular senescence under various conditions

2024-02-13

Abstract excerpt

<title>Abstract</title> <p>Despite the manifestation and contribution of cellular senescence to tissue aging and aging-related disease, the identification of <italic>in vivo </italic>senescent cells and the recognition of senescence-specific communication still remain challenging. Current senescence evaluation methods rely greatly on expression level of well-known senescence markers, enrichment of aging-related g...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6b616faf-9ca1-5795-9462-c5a8f4cc3f8f
DOI: 10.21203/rs.3.rs-3920908/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Robust senescence evaluation by transcriptome-based hUSI to facilitate characterizing cellular senescence under various conditionsDOI 10.21203/rs.3.rs-3920908/v1Read

A transcriptome-based human universal senescence index (hUSI) robustly predicts cellular senescence under various conditionsSemantic proximity Read

Unveiling the cell-type-specific landscape of cellular senescence through single-cell transcriptomics using SenePySemantic proximity Read

<i>SenePy</i> : Unveiling the Cell-Type Specific Landscape of Cellular Senescence through Single-Cell Analysis in Living OrganismsSemantic proximity Read

An updated landscape of cellular senescence heterogeneity: Mechanisms, technologies and senotherapiesSemantic proximity Read

SenCat: Cataloging human cell senescence through multiomic profiling of multiple senescent primary cell typesSemantic proximity Read

Exploring Senescence-Related Transcriptional Signatures to Uncover Molecular Subtypes and Key Genes in Hepatocellular CarcinomaSemantic proximity Read

Transcriptome signature of cellular senescenceSemantic proximity Read

A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across TissuesSemantic proximity Read

Senescence as a Dictator of Patient Outcomes and Therapeutic Efficacies in Human Gastric CancerSemantic proximity Read

A Multidimensional Systems Biology Analysis of Cellular Senescence in Ageing and DiseaseSemantic proximity Read

SenSet, a novel human lung senescence cell gene signature, identifies cell-specific senescence mechanismsSemantic proximity Read

Emerging insights in senescence: pathways from preclinical models to therapeutic innovationsSemantic proximity Read