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Article

Distinct Mechanisms Determine α-Synuclein Fibril Morphology during Growth and Maturation.

ACS chemical neuroscience - 15 Mar 2017

Sidhu Arshdeep, Segers-Nolten Ine, Raussens Vincent, Claessens Mireille M A E, Subramaniam Vinod

Abstract excerpt

Amyloid polymorphs have become one of the focal points of molecular studies of neurodegenerative diseases like Parkinson's disease. Due to their distinct biochemical properties and prion-like characteristics, insights into the molecular origin and stability of amyloid polymorphs over time are crucial for understanding the potential role of amyloid polymorphism in these diseases. Here, we systematically study the...

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PMID: 28292187
DOI: 10.1021/acschemneuro.6b00287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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