Article
An mRNA decapping mutant deficient in P body assembly limits mRNA stabilization in response to osmotic stress.
Scientific reports - 14 Mar 2017
Huch Susanne, Nissan Tracy
Abstract excerpt
Yeast is exposed to changing environmental conditions and must adapt its genetic program to provide a homeostatic intracellular environment. An important stress for yeast in the wild is high osmolarity. A key response to this stress is increased mRNA stability primarily by the inhibition of deadenylation. We previously demonstrated that mutations in decapping activators (edc3∆ lsm4∆C), which result in defects in...
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