Article
Sbp1p affects translational repression and decapping in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Jul 2006
Segal Scott P, Dunckley Travis, Parker Roy
Abstract excerpt
The relationship between translation and mRNA turnover is critical to the regulation of gene expression. One major pathway for mRNA turnover occurs by deadenylation, which leads to decapping and subsequent 5'-to-3' degradation of the body of the mRNA. Prior to mRNA decapping, a transcript exits translation and enters P bodies to become a potential decapping substrate. To understand the transition from translation...
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