Article
The role of follicular T helper cells in patients with malignant lymphoid disease.
Hematology (Amsterdam, Netherlands) - 1 Aug 2017
Zhou Dong-Ming, Xu Yan-Xia, Zhang Li-Ying, Sun Yu, Wang Zi-Yan, Yuan Yu-Qing, Fu Jin-Xiang
Abstract excerpt
OBJECTIVES: To investigate the dynamic change of follicular T helper cells (TFH) in patients with malignant lymphoid disease (MLD) and to explore its clinical significance. METHODS: The dynamic change of TFH cells, ICOS+- and PD-1+ TFH cells at pretreatment and different treatment periods was determined by flow cytometry in 85 MLD patients. Concentration of interleukin 21 (IL-21) was evaluated by ELISA, and the...
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