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Article

Biology and clinical relevance of follicular cytotoxic T cells

14 Dec 2022

Abstract excerpt

Follicular cytotoxic T (Tfc) cells are a newly identified subset of CD8+ T cells enriched in B cell follicles and their surroundings, which integrate multiple functions such as killing, memory, supporting and regulation. Tfc cells share similarities with follicular helper T (Tfh) cells, conventional cytotoxic CD8+ T (Tc cells)cells and follicular regulatory T (Tfr) cells, while they express distinct transcription...

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PMID: 36591286
DOI: 10.3389/fimmu.2022.1036616

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