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Article

Phenotypic and functional characteristics of IL-21-expressing CD8(+) T cells in human nasal polyps.

Scientific reports - 29 Jul 2016

Xiao Li, Jia Lei, Bai Lu, He Long, Yang Binyan, Wu Changyou, Li Huabin

Abstract excerpt

Although CD4(+) T cells are recognized to play an important role in the inflammatory response of nasal polyps (NPs), the biological functions of CD8(+) T cells in polypogenesis remain unclear. In this study, we analyzed cell markers, cytokine expression and transcription factors in IL-21-expressing CD8(+) T cells in polyp tissues of NP patients. The results showed that the majority of IL-21-producing CD8(+) T...

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Identifiers

PMID: 27468819
DOI: 10.1038/srep30362
PMCID: PMC4965861

Genes

CXCR5
ICOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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