Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits.

doi:10.1016/j.ajhg.2017.01.027

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Article

Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits.

American journal of human genetics - 2 Mar 2017

Civelek Mete, Wu Ying, Pan Calvin, Raulerson Chelsea K, Ko Arthur, He Aiqing, Tilford Charles, Saleem Niyas K, Stančáková Alena, Scott Laura J, Fuchsberger Christian, Stringham Heather M, Jackson Anne U, Narisu Narisu, Chines Peter S, Small Kerrin S, Kuusisto Johanna, Parks Brian W, Pajukanta Päivi, Kirchgessner Todd, Collins Francis S, Gargalovic Peter S, Boehnke Michael, Laakso Markku, Mohlke Karen L, Lusis Aldons J

Abstract excerpt

Subcutaneous adipose tissue stores excess lipids and maintains energy balance. We performed expression quantitative trait locus (eQTL) analyses by using abdominal subcutaneous adipose tissue of 770 extensively phenotyped participants of the METSIM study. We identified cis-eQTLs for 12,400 genes at a 1% false-discovery rate. Among an approximately 680 known genome-wide association study (GWAS) loci for...

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Identifiers

PMID: 28257690
DOI: 10.1016/j.ajhg.2017.01.027
PMCID: PMC5339333

Genes

CIITA
KLF14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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