Article
Influence of IL-18 and IL-10 Polymorphisms on Tacrolimus Elimination in Chinese Lung Transplant Patients.
Disease markers - 1 Jan 2017
Zhang Xiaoqing, Xu Jiandong, Fan Junwei, Zhang Tao, Li Yuping, Xie Boxiong, Zhang Wei, Lin Shengtao, Ye Ling, Liu Yuan, Jiang Gening
Abstract excerpt
Aims. The influence of interleukin-10 (IL-10) and interleukin-18 (IL-18) polymorphisms on tacrolimus pharmacokinetics had been described in liver and kidney transplantation. The expression of cytokines varied in different kinds of transplantation. The influence of IL-10 and IL-18 genetic polymorphisms on the pharmacokinetic parameters of tacrolimus remains unclear in lung transplantation. Methods. 51 lung...
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