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Article

Genotype-Guided Model for Prediction of Tacrolimus Initial Dosing After Lung Transplantation.

Journal of clinical pharmacology - 1 Jun 2024

Du Wenwen, Wang Xiaoxing, Zhang Dan, Zuo Xianbo

Abstract excerpt

The determination of the appropriate initial dose for tacrolimus is crucial in achieving the target concentration promptly and avoiding adverse effects and poor prognosis. However, the trial-and-error approach is still common practice. This study aimed to establish a prediction model for an initial dosing algorithm of tacrolimus in patients receiving a lung transplant. A total of 210 lung transplant recipients...

Read the complete abstract on PubMed

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Share to Cytochrome P-450 CYP3A
Share to Dose-Response Relationship, Drug

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Immunosuppressive Agents

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 38327217
DOI: 10.1002/jcph.2411

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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