Article
Population pharmacokinetics of tacrolimus and CYP3A5, MDR1 and IL-10 polymorphisms in adult liver transplant patients.
Journal of clinical pharmacy and therapeutics - 1 Oct 2007
Li D, Lu W, Zhu J-Y, Gao J, Lou Y-Q, Zhang G-L
Abstract excerpt
BACKGROUND AND OBJECTIVE: Tacrolimus, an immunosuppressant widely used after liver transplantation, is characterized by a large inter-individual variability in its pharmacokinetics. The aim of this study was to perform population pharmacokinetic analysis of oral tacrolimus in liver transplant rec...
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