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Article

Impact of interleukin-10 gene polymorphisms on tacrolimus dosing requirements in Chinese liver transplant patients during the early posttransplantation period.

European journal of clinical pharmacology - 1 Aug 2011

Zhang Xiaoqing, Wang Zhaowen, Fan Junwei, Liu Gaolin, Peng Zhihai

Abstract excerpt

AIM: Pharmacogenetics holds the potential to elucidate the inherited basis of differences between individual responses to drugs. Impacts of CYP3A5 and ABCB1 gene polymorphisms on the immunosuppressant tacrolimus have been reported in previous studies of liver transplantation. The functions of interleukin-10 (IL-10) gene expression are complex in the early period after liver transplantation. In this study, we...

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Identifiers

PMID: 21359536
DOI: 10.1007/s00228-011-0993-8

Genes

ABCB1

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