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Article

The role of variant histone H2AV in Drosophila melanogaster larval hematopoiesis.

Development (Cambridge, England) - 15 Apr 2017

Grigorian Melina, DeBruhl Heather, Lipsick Joseph S

Abstract excerpt

Replication-independent histone variants can replace the canonical replication-dependent histones. Vertebrates have multiple H2A variant histones, including H2AZ and H2AX that are present in most eukaryotes. H2AZ regulates transcriptional activation as well as the maintenance of gene silencing, while H2AX is important in DNA damage repair. The fruit fly Drosophila melanogaster has only one histone H2A variant...

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Identifiers

PMID: 28242611
DOI: 10.1242/dev.142729
PMCID: PMC5399662

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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