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Article

The embryonic linker histone H1 variant of Drosophila, dBigH1, regulates zygotic genome activation.

Developmental cell - 30 Sept 2013

Pérez-Montero Salvador, Carbonell Albert, Morán Tomás, Vaquero Alejandro, Azorín Fernando

Abstract excerpt

Histone H1 is an essential chromatin component. Metazoans usually contain multiple stage-specific H1s. In particular, specific variants replace somatic H1s during early embryogenesis. In this regard, Drosophila was an exception because a single dH1 was identified that, starting at cellularization, is detected throughout development in somatic cells. Here, we identify the embryonic H1 of Drosophila, dBigH1. dBigH1...

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PMID: 24055651
DOI: 10.1016/j.devcel.2013.08.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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