Article
Quantitative Measurement of Histone Tail Acetylation Reveals Stage-Specific Regulation and Response to Environmental Changes during Drosophila Development.
Biochemistry - 22 Mar 2016
Henry Ryan A, Singh Tanu, Kuo Yin-Ming, Biester Alison, O'Keefe Abigail, Lee Sandy, Andrews Andrew J, O'Reilly Alana M
Abstract excerpt
Histone modification plays a major role in regulating gene transcription and ensuring the healthy development of an organism. Numerous studies have suggested that histones are dynamically modified during developmental events to control gene expression levels in a temporal and spatial manner. However, the study of histone acetylation dynamics using currently available techniques is hindered by the difficulty of...
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