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Interactions Between the Histone Variant H2Av and the Suppressor of Hairy wing Insulator Influence the DNA Damage Response and Lymph Gland Development in <i>Drosophila</i>

2023-06-02

Abstract excerpt

Genome architecture is regulated by chromatin insulator proteins, and misregulation of insulator function is associated with genome instability and transcriptional regulatory defects in both vertebrates and Drosophila . Indeed, mutations of the sole insulator protein in humans, CTCF, are carcinogenic and mutations in the Drosophila insulator protein Suppressor of Hairy wing [Su(Hw)] lead to chromosomal rearrang...

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Literature Corpus work
bce5f5b2-f2e6-50d1-9f53-126b1993a24c
DOI
10.1101/2023.05.31.543180
Open publication

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Interactions Between the Histone Variant H2Av and the Suppressor of Hairy wing Insulator Influence the DNA Damage Response and Lymph Gland Development in <i>Drosophila</i>DOI 10.1101/2023.05.31.543180
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