Article

Non-redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progression

2020-09-15

Abstract excerpt

<h4>SUMMARY</h4> H2A.Z is a H2A-type histone variant essential for many aspects of cell biology ranging from gene expression to genome stability. From deuterostomes, H2A.Z evolved into two paralogues H2A.Z.1 and H2A.Z.2 that differ by only three amino acids and are encoded by different genes ( H2AFZ and H2AFV respectively). Despite the importance of this histone variant in development and cellular homeostasis,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2af82fb6-549d-5e70-ae3c-0866203af242
DOI: 10.1101/2020.09.15.297671

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Non-redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progressionDOI 10.1101/2020.09.15.297671Read

H2A.Z functions to regulate progression through the cell cycle.Semantic proximity Read

Histone variant H2A.Z facilitates DNA replication.Semantic proximity Read

The evolutionary differentiation of two histone H2A.Z variants in chordates (H2A.Z-1 and H2A.Z-2) is mediated by a stepwise mutation process that affects three amino acid residues.Semantic proximity Read

Replacement of Arabidopsis H2A.Z with human H2A.Z orthologs reveals extensive functional conservation and limited importance of the N-terminal tail sequence for Arabidopsis developmentSemantic proximity Read

Key functional regions in the histone variant H2A.Z C-terminal docking domain.Semantic proximity Read

Short Histone H2A Variants: Small in Stature but not in Function.Semantic proximity Read

The H2A.Z histone variant integrates Wnt signaling in intestinal epithelial homeostasisSemantic proximity Read

Histone variants in development and diseases.Semantic proximity Read

Histone H3.3 maintains genome integrity during mammalian development.Semantic proximity Read

H2A monoubiquitination: insights from human genetics and animal modelsSemantic proximity Read

[H2A.Z: a histone variant that decorates gene promoters].Semantic proximity Read

Global H3.3 dynamic deposition defines its bimodal role in cell fate transitionSemantic proximity Read