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Article

Tuned SMC Arms Drive Chromosomal Loading of Prokaryotic Condensin.

Molecular cell - 2 Mar 2017

Bürmann Frank, Basfeld Alrun, Vazquez Nunez Roberto, Diebold-Durand Marie-Laure, Wilhelm Larissa, Gruber Stephan

Abstract excerpt

SMC proteins support vital cellular processes in all domains of life by organizing chromosomal DNA. They are composed of ATPase "head" and "hinge" dimerization domains and a connecting coiled-coil "arm." Binding to a kleisin subunit creates a closed tripartite ring, whose ∼47-nm-long SMC arms act as barrier for DNA entrapment. Here, we uncover another, more active function of the bacterial Smc arm. Using...

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Identifiers

PMID: 28238653
DOI: 10.1016/j.molcel.2017.01.026
PMCID: PMC5344682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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