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Article

A biomechanical mechanism for initiating DNA packaging.

Nucleic acids research - 29 Oct 2014

Wang Haowei, Yehoshua Samuel, Ali Sabrina S, Navarre William Wiley, Milstein Joshua N

Abstract excerpt

The bacterial chromosome is under varying levels of mechanical stress due to a high degree of crowding and dynamic protein-DNA interactions experienced within the nucleoid. DNA tension is difficult to measure in cells and its functional significance remains unclear although in vitro experiments have implicated a range of biomechanical phenomena. Using single-molecule tools, we have uncovered a novel protein-DNA...

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PMID: 25274732
DOI: 10.1093/nar/gku896
PMCID: PMC4231757

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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