Article
High-Throughput Genomic Profiling of Adult Solid Tumors Reveals Novel Insights into Cancer Pathogenesis.
Cancer research - 1 May 2017
Hartmaier Ryan J, Albacker Lee A, Chmielecki Juliann, Bailey Mark, He Jie, Goldberg Michael E, Ramkissoon Shakti, Suh James, Elvin Julia A, Chiacchia Samuel, Frampton Garrett M, Ross Jeffrey S, Miller Vincent, Stephens Philip J, Lipson Doron
Abstract excerpt
Genomic profiling is widely predicted to become a standard of care in clinical oncology, but more effective data sharing to accelerate progress in precision medicine will be required. Here, we describe cancer-associated genomic profiles from 18,004 unique adult cancers. The dataset was composed of 162 tumor subtypes including multiple rare and uncommon tumors. Comparison of alteration frequencies to The Cancer...
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