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Genomic landscape of adenosquamous carcinoma of the colorectum reveals actionable therapeutic targets

2026-06-11

Abstract excerpt

<title>Abstract</title> <p>Colorectal adenosquamous carcinoma (ASC) is an extremely rare and aggressive subtype accounting for merely 0.06% of all colorectal malignancies, with its genomic features and clinical therapeutic targets remaining largely unelucidated. This study aimed to characterize the unique genomic mutational landscape of ASC and identify clinically actionable therapeutic targets via whole-exome se...

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Literature Corpus work
62138858-a357-550f-aa2c-0824e6fcbb2a
DOI
10.21203/rs.3.rs-9757503/v1
Open publication

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Genomic landscape of adenosquamous carcinoma of the colorectum reveals actionable therapeutic targetsDOI 10.21203/rs.3.rs-9757503/v1
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