Article
Fatty acid amide hydrolase inhibitors produce rapid anti-anxiety responses through amygdala long-term depression in male rodents.
Journal of psychiatry & neuroscience : JPN - 1 Jun 2017
Duan Tingting, Gu Ning, Wang Ying, Wang Feng, Zhu Jie, Fang Yiru, Shen Yuan, Han Jing, Zhang Xia
Abstract excerpt
BACKGROUND: Pathological anxiety is the most common type of psychiatric disorder. The current first-line anti-anxiety treatment, selective serotonin/noradrenaline reuptake inhibitors, produces a delayed onset of action with modest therapeutic and substantial adverse effects, and long-term use of the fast-acting anti-anxiety benzodiazepines causes severe adverse effects. Inhibition of the fatty acid amide...
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