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Article

Elevated Brain Fatty Acid Amide Hydrolase Induces Depressive-Like Phenotypes in Rodent Models: A Review.

International journal of molecular sciences - 21 Jan 2021

Rafiei Dorsa, Kolla Nathan J

Abstract excerpt

Altered activity of fatty acid amide hydrolase (FAAH), an enzyme of the endocannabinoid system, has been implicated in several neuropsychiatric disorders, including major depressive disorder (MDD). It is speculated that increased brain FAAH expression is correlated with increased depressive symptoms. The aim of this scoping review was to establish the role of FAAH expression in animal models of depression to...

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Identifiers

PMID: 33494322
DOI: 10.3390/ijms22031047
PMCID: PMC7864498

Genes

FAAH

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