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Article

A myeloid tumor suppressor role for NOL3

23 Feb 2017

Abstract excerpt

Despite the identification of several oncogenic driver mutations leading to constitutive JAK–STAT activation, the cellular and molecular biology of myeloproliferative neoplasms (MPN) remains incompletely understood. Recent discoveries have identified underlying disease-modifying molecular aberrations contributing to disease initiation and progression. Here, we report that deletion of Nol3 (Nucleolar protein 3) in...

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PMID: 28232469
DOI: 10.1084/jem.20162089

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