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Article

Genetic variation of the Toll-like receptors in a Swedish allergic rhinitis case population.

BMC medical genetics - 23 Feb 2017

Henmyr V, Carlberg D, Manderstedt E, Lind-Halldén C, Säll T, Cardell L O, Halldén C

Abstract excerpt

BACKGROUND: Variation in the 10 toll-like receptor (TLR) genes has been significantly associated with allergic rhinitis (AR) in several candidate gene studies and three large genome-wide association studies. These have all investigated common variants, but no investigations for rare variants (MAF ≤ 1%) have been made in AR. The present study aims to describe the genetic variation of the promoter and coding...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

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Source

Open in PubMed Open full text

Identifiers

PMID: 28228119
DOI: 10.1186/s12881-017-0379-6
PMCID: PMC5322632

Genes

TLR1
TLR10
TLR7
MAF
TLR5
TLR6
TLR9
TLR8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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