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Article

Rare TLR2 mutations reduce TLR2 receptor function and can increase atopy risk.

Allergy - 1 Apr 2009

Kormann M S D, Ferstl R, Depner M, Klopp N, Spiller S, Illig T, Vogelberg C, von Mutius E, Kirschning C J, Kabesch M

Abstract excerpt

BACKGROUND: Common genetic variations in toll-like receptor 2 (TLR2), an innate pathogen recognition receptor, may influence the development of atopic diseases. So far, very little is known about the role of rare TLR2 mutations in these diseases. OBJECTIVE: We investigated the functional properti...

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Source

Identifiers

PMID: 19220214
DOI: 10.1111/j.1398-9995.2008.01891.x

Genes

TLR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19220214-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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