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Article

Association analysis identifies TLR7 and TLR8 as novel risk genes in asthma and related disorders.

Thorax - 1 Dec 2008

Møller-Larsen S, Nyegaard M, Haagerup A, Vestbo J, Kruse T A, Børglum A D

Abstract excerpt

BACKGROUND: Toll-like receptors (TLRs) are structurally and functionally related and play important roles in the innate and adaptive immune system. By genome scanning, evidence of linkage between chromosome Xp22 and asthma and related atopic disorders has previously been obtained. Xp22 harbours the TLR7 and TLR8 genes. METHODS: The involvement of TLR7 and TLR8 in the aetiology of asthma and related disorders was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18682521
DOI: 10.1136/thx.2007.094128

Genes

TLR7
TLR8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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