Article
Association of the toll-like receptor 2 A-16934T promoter polymorphism with severe atopic dermatitis.
Allergy - 1 Nov 2009
Oh D-Y, Schumann R R, Hamann L, Neumann K, Worm M, Heine G
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease with a multifactorial pathogenesis and increasing incidence in the Western world. A genetically determined defective function of pattern recognition receptors such as toll-like receptors (TLRs) has been proposed as a candidate mechanism in the pathogenesis of AD. AIM: To study the impact of genetic predisposition of five genes encoding for...
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