Article
Extent of field change in colorectal cancers with BRAF mutation.
Singapore medical journal - 1 Mar 2018
Poh Aaron, Chang Heidi Sian Ying, Tan Kok Yang, Sam Xin Xiu, Khoo Avery, Choo Shoa Nian, Nga Min En, Wan Wei Keat
Abstract excerpt
INTRODUCTION: Sporadic colorectal cancers with BRAF mutations constitute two distinct subgroups of colorectal cancers. Recent studies have linked the presence of the BRAF mutation to a familial inheritance pattern. This was a proof-of-concept study that aimed to examine: (a) the extent of field change in sporadic colorectal cancers with BRAF mutation; and (b) the extent of resection margins required and the...
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