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Article

Field Cancerization in Sporadic Colon Cancer

25 Apr 2016

Abstract excerpt

BACKGROUND/AIMS: Aberrant DNA methylation has a specific role in field cancerization. Certain molecular markers, including secreted frizzled-related protein 2 (SFRP2), tissue factor pathway inhibitor 2 (TFPI2 ), N-Myc downstream-regulated gene 4 (NDRG4) and bone morphogenic protein 3 (BMP3), have previously been shown to be hypermethylated in colorectal cancer (CRC). We aim to examine field cancerization in CRC...

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Share to Epigenetics and DNA Methylation
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PMID: 27114416
DOI: 10.5009/gnl15334

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