Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Breast cancer risk prediction using a clinical risk model and polygenic risk score.

Breast cancer research and treatment - 1 Oct 2016

Shieh Yiwey, Hu Donglei, Ma Lin, Huntsman Scott, Gard Charlotte C, Leung Jessica W T, Tice Jeffrey A, Vachon Celine M, Cummings Steven R, Kerlikowske Karla, Ziv Elad

Abstract excerpt

Breast cancer risk assessment can inform the use of screening and prevention modalities. We investigated the performance of the Breast Cancer Surveillance Consortium (BCSC) risk model in combination with a polygenic risk score (PRS) comprised of 83 single nucleotide polymorphisms identified from genome-wide association studies. We conducted a nested case-control study of 486 cases and 495 matched controls within...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Risk Assessment
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Area Under Curve

Share to Bayes Theorem

Share to Breast Neoplasms

Share to Genome-Wide Association Study

Share to Logistic Models

Share to Multifactorial Inheritance

Source

Open in PubMed Open full text

Identifiers

PMID: 27565998
DOI: 10.1007/s10549-016-3953-2
PMCID: PMC5033764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Breast cancer risk prediction using a clinical risk model and polygenic risk score.PMID 27565998Read ↗

Polygenic Risk Scores for Breast Cancer: Modern Approaches to Risk Prediction and Subtype Identification.Semantic proximity Read ↗

Polygenic risk scores and breast cancer risk prediction.Semantic proximity Read ↗

Polygenic risk scores to refine Breast cancer screening and prevention strategies.Semantic proximity Read ↗

Polygenic risk scores for prediction of breast cancer risk in Asian populations.Semantic proximity Read ↗

Incorporating Polygenic Risk Scores and Nongenetic Risk Factors for Breast Cancer Risk Prediction Among Asian Women.Semantic proximity Read ↗

European polygenic risk score for prediction of breast cancer shows similar performance in Asian women.Semantic proximity Read ↗

The contributions of breast density and common genetic variation to breast cancer risk.Semantic proximity Read ↗

Development of a Breast Cancer Risk Prediction Model Integrating Monogenic, Polygenic, and Epidemiologic Risk.Semantic proximity Read ↗

A polygenic risk score for breast cancer risk in a Taiwanese population.Semantic proximity Read ↗

Breast cancer risk prediction using a polygenic risk score in the familial setting: a prospective study from the Breast Cancer Family Registry and kConFab.Semantic proximity Read ↗

Polygenic risk score-based prediction of breast cancer risk in Taiwanese women with dense breast using a retrospective cohort study.Semantic proximity Read ↗

Development and Validation of a Clinical Polygenic Risk Score to Predict Breast Cancer RiskSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.