Article
The largest genome-wide association study for breast cancer in Taiwanese Han population.
Breast cancer research and treatment - 1 Jan 2024
Hsu Yu-Ching, Chen Hung-Lin, Cheng Chi-Fung, Chattopadhyay Amrita, Chen Pei-Shan, Lin Che-Chen, Chiang Hsiu-Yin, Liu Ting-Yuan, Huang Chi-Hao, Kuo Chin-Chi, Chuang Eric Y, Lu Tzu-Pin, Tsai Fuu-Jen
Abstract excerpt
PURPOSE: Breast cancer is a molecularly heterogeneous disease, and multiple genetic variants contribute to its development and prognosis. Most of previous genome-wide association studies (GWASs) and polygenic risk scores (PRSs) analyses focused on studying breast cancers of Caucasian populations, which may not be applicable to other population. Therefore, we conducted the largest breast cancer cohort of Taiwanese...
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