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Article

New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jun 2017

Naruse Chie, Shibata Shinwa, Tamura Masaru, Kawaguchi Takayuki, Abe Kanae, Sugihara Kazushi, Kato Tomoaki, Nishiuchi Takumi, Wakana Shigeharu, Ikawa Masahito, Asano Masahide

Abstract excerpt

Jmjd3 and Utx are demethylases specific for lysine 27 of histone H3. Previous reports indicate that Jmjd3 is essential for differentiation of various cell types, such as macrophages and epidermal cells in mice, whereas Utx is involved in cancer and developmental diseases in humans and mice, as well as Hox regulation in zebrafish and nematodes. Here, we report that Jmjd3, but not Utx, is involved in axial skeletal...

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PMID: 28188179
DOI: 10.1096/fj.201600642R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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