Article
Jmjd3 controls mesodermal and cardiovascular differentiation of embryonic stem cells.
Circulation research - 13 Sept 2013
Ohtani Kisho, Zhao Cong, Dobreva Gergana, Manavski Yosif, Kluge Britta, Braun Thomas, Rieger Michael A, Zeiher Andreas M, Dimmeler Stefanie
Abstract excerpt
RATIONALE: The developmental role of the H3K27 demethylases Jmjd3, especially its epigenetic regulation at target genes in response to upstream developmental signaling, is unclear. OBJECTIVE: To determine the role of Jmjd3 during mesoderm and cardiovascular lineage commitment. METHODS AND RESULTS...
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