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Article

Gene expression and epigenetic aberrations in F1‐placentas fathered by obese males

10 Feb 2017

Abstract excerpt

Gene expression and/or epigenetic deregulation may have consequences for sperm and blastocysts, as well as for the placenta, together potentially contributing to problems observed in offspring. We previously demonstrated specific perturbations of fertilization, blastocyst formation, implantation, as well as aberrant glucose metabolism and adiposity in offspring using a mouse model of paternal obesity. The current...

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PMID: 28186371
DOI: 10.1002/mrd.22784

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