Article
Epigenetic Changes Associated With Obesity-related Metabolic Comorbidities
8 Jul 2025
Abstract excerpt
Obesity arises from a complex interaction of genetic, hormonal, dietary, and behavioral factors that drive chronic energy imbalance, excessive fat accumulation, systemic inflammation, and insulin resistance, thus increasing the risk of metabolic diseases. Recent evidence suggests a significant role for epigenetic mechanisms, such as changes in patterns of DNA methylation, histone modifications, and chromatin...
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