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Article

MED12 is recurrently mutated in Middle Eastern colorectal cancer.

Gut - 1 Apr 2018

Siraj Abdul K, Masoodi Tariq, Bu Rong, Pratheeshkumar Poyil, Al-Sanea Nasser, Ashari Luai H, Abduljabbar Alaa, Alhomoud Samar, Al-Dayel Fouad, Alkuraya Fowzan S, Al-Kuraya Khawla S

Abstract excerpt

OBJECTIVE: Colorectal cancer (CRC) is a common cancer and a leading cause of cancer deaths. Previous studies have identified a number of key steps in the evolution of CRC but our knowledge of driver mutations in CRC remains incomplete. Recognising the potential of studying different human populations to reveal novel insights in disease pathogenesis, we conducted genomic analysis of CRC in Saudi patients. DESIGN:...

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Source

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Identifiers

PMID: 28183795
DOI: 10.1136/gutjnl-2016-313334
PMCID: PMC5868237

Genes

MED12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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