Article
Analysis Of Common Somatic Mutations In Colorectal Carcinoma And Associated Dysregulated Pathwaysarts.
Journal of Ayub Medical College, Abbottabad : JAMC - 1 Jan 2000
Hassan Sobia, Khatoon Ambrina, Bukhari Uzma, Mirza Talat
Abstract excerpt
BACKGROUND: Identification of gene targets and biological pathways involved in colorectal carcinoma (CRC) is essential for better management of patients. Our study aims to highlight common somatic mutations in colorectal carcinoma and to identify dysregulated pathways and gene enrichment based on KRAS and BRAF interaction network analysis. METHODS: By using cancer browser tool in COSMIC database, mutation...
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