Whole-Genome Profiles of Malay Colorectal Cancer Patients with Intact MMR Proteins.

doi:10.3390/genes12091448

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Whole-Genome Profiles of Malay Colorectal Cancer Patients with Intact MMR Proteins.

Genes - 20 Sept 2021

Juhari Wan Khairunnisa Wan, Ahmad Amin Noordin Khairul Bariah, Zakaria Andee Dzulkarnaen, Rahman Wan Faiziah Wan Abdul, Mokhter Wan Muhamad Mokhzani Wan Muhamad, Hassan Muhammad Radzi Abu, Sidek Ahmad Shanwani Mohammed, Zilfalil Bin Alwi

Abstract excerpt

BACKGROUND: This study aimed to identify new genes associated with CRC in patients with normal mismatch repair (MMR) protein expression. METHOD: Whole-genome sequencing (WGS) was performed in seven early-age-onset Malay CRC patients. Potential germline genetic variants, including single-nucleotide variations and insertions and deletions (indels), were prioritized using functional and predictive algorithms....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms
Share to DNA Mismatch Repair
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Malaysia

Share to Mutation

Share to Proteins

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 34573430
DOI: 10.3390/genes12091448
PMCID: PMC8471947

Provenance

PubMed metadata and Literature Corpus relationships.