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Article

Rapamycin and the inhibition of the secretory phenotype.

Experimental gerontology - 1 Aug 2017

Wang Rong, Sunchu Bharath, Perez Viviana I

Abstract excerpt

Senescent cells contribute to age-related pathology and loss of function, and their selective removal improves physiological function and extends longevity. Cell senescence is a complex process that can be triggered by multiple challenges. Recently it has been observed that the composition of the secretory phenotype or SASP depends on the insult that triggers cell senescence. Rapamycin, an inhibitor of mTOR that...

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Identifiers

PMID: 28167236
DOI: 10.1016/j.exger.2017.01.026

Genes

MAPKAPK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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