Article
Combining omics data to identify genes associated with allergic rhinitis.
Clinical epigenetics - 1 Jan 2017
Morin Andréanne, Laviolette Michel, Pastinen Tomi, Boulet Louis-Philippe, Laprise Catherine
Abstract excerpt
Allergic rhinitis is a common chronic disorder characterized by immunoglobulin E-mediated inflammation. To identify new genes associated with this trait, we performed genome- and epigenome-wide association studies and linked marginally significant CpGs located in genes or its promoter and SNPs located 1 Mb from the CpGs, by identifying cis methylation quantitative trait loci (mQTL). This approach relies on...
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