Article
Association between DNA hypomethylation at IL13 gene and allergic rhinitis in house dust mite-sensitized subjects.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Feb 2016
Li J Y, Zhang Y, Lin X P, Ruan Y, Wang Y, Wang C S, Zhang L
Abstract excerpt
BACKGROUND: Allergic rhinitis (AR) is a complex disease, in which gene-environment interactions contribute to its pathogenesis. Epigenetic modifications such as DNA methylation play an important role in the regulation of gene function. As IL13, a pleiotropic cytokine, may be important in conferring susceptibility to AR, the aim of the present work was to assess the relationship between a CpG island methylation...
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