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Article

The Immunogenetic Landscape of Allergic Rhinitis: from Cellular Effectors to Gene Regulation and Targeted Therapies.

International journal of biological sciences - 1 Jan 2026

Zhang Xu, Zhang Zhiqiang, Peng Qian, Huang Xinyu, Liu Mengyuan, Bai Daoming, Yang Rui, Zhang Yun, Yang Chunping

Abstract excerpt

Allergic Rhinitis (AR) is a highly prevalent type 2 inflammatory disease driven by a complex immunogenetic background. This review aims to systematically delineate the immunogenetic landscape of AR, elucidating the complete knowledge chain from macroscopic cellular interactions and microscopic molecular regulation to precision targeted therapies. The article first dissects the two core immune axes driving the...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41608632
DOI: 10.7150/ijbs.126788
PMCID: PMC12837821

Genes

AR
TSLP
FLG
GATA3
STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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